Dr. Anindita Saha

Dr. Anindita Saha defended her thesis titled “Process Development of Scalable Solution Cocrystallization Technique” on 31st October 2025.

Anindita’s work involved extensive thermodynamic and kinetic studies on solution-based cocrystallization process, including both cooling and slurry methods. She has worked on identifying and utilizing ternary phase diagrams of multi-component systems for developing robust cocrystallization conditions. In collaboration with Prof. Sameer Dalvi (IIT Gandhinagar), she utilized in-situ Raman probe for time-resolved monitoring of crystallization process. Combining in-situ tools like turbidity probe and Raman probes along with offline PXRD analysis, she explored the mechanism of cocrystal nucleation. Moving from the small-scale (20-60 mL studies), she scaled up the crystallization to 2 L scale and demonstrated scalability and robustness of solution-based cocrystallization technique.

I believe the goal of researchers should be commitment towards making the best use of resources and to protect the environment, improving lives and revitalizing communities. I love travelling and photography and a huge Agatha Christie fan.

Educational Qualifications:

  • Ph.D. from IIT Patna (2021-2025)
  • M.Tech., Chemical Engineering (2018-2020) from Malaviya National Institute of Technology, Jaipur
  • B.Tech., Biotechnology (2014-2018) from GITAM University, Visakhapatnam

Journal Publications:

  • Pawar, N., Saha, A., Nandan, N., Parambil, J. V., (2021) Solution Cocrystallization: A Scalable Approach for Cocrystal Production. Crystals, 11(3), 303. (https://doi.org/10.3390/cryst11030303)
  • Saha, A., Ahangar, A. A., Dar, A. A., Thirunahari, S., Parambil, J. V. (2023). Pharmaceutical Cocrystals: A Perspective on Development and Scale-up of Solution Cocrystallization, Crystal Growth and Design. (https://doi.org/10.1021/acs.cgd.2c01553)
  • Saha, A., Dalvi, S. V., Dar, A. A., & Parambil, J. V. (2024). Ternary phase diagram and investigation of slurry conversion of 1: 1 sulfamethazine-acetylsalicylic acid cocrystal. Chemical Engineering Research and Design, 210, 71-81. (https://doi.org/10.1016/j.cherd.2024.08.017)
  • Saha, A., Dalvi, S. V., Dar, A. A., & Parambil, J. V. (2025). Cooling Crystallization of Sulfamethazine-Acetylsalicylic Acid Cocrystal: Estimating Nucleation Kinetics and Real-Time Phase Identification. Crystal Growth & Design, 25, 12, 4521–4530. (https://doi.org/10.1021/acs.cgd.5c00433)
  • Saha, A., & Parambil, J. V. (2026). Non-monotonic metastable zone-width behavior in cooling cocrystallization: a case study on the sulfamethazine-acetylsalicylic acid cocrystal system. CrystEngComm, 28(1), 83-87. (https://doi.org/10.1039/D5CE00822K)

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